MILPITAS — Cisco Systems has decided to eliminate 221 jobs at two Bay Area locations, the company disclosed in WARN notices it sent to the state Employment Development Department.

The cuts consist of 157 layoffs at a site in Milpitas and another 64 in San Francisco, WARN notices show.

San Jose-based Cisco stated the layoffs were scheduled to take effect on Oct. 13, according to the WARN letters. They were all described as permanent.

“None of the affected employees are represented by a union, nor do any have bumping rights applicable to the positions in question,” a Cisco executive stated in the WARN letter.

Cisco previously had layoffs in November 2024.

With the latest round of cuts, Cisco has disclosed plans to eliminate about 2,870 jobs in the Bay Area over a period that covers 2022 through August.