SAN DIEGO — All in all, Monday will go down one of the most unique days of Heliot Ramos’ career.

His comments about Giants fans were misinterpreted and taken out of context. His leadoff home run kickstarted a three-homer first inning and the Giants’ 4-3 win over the San Diego Padres. His embracing of the villain role at Petco Park after being involved in a fan interference call. It all amounted to whirlwind of a day, one that may never be duplicated.

On Monday morning, the San Francisco Chronicle released a story in which Ramos told the publication that the Giants’ recent stretch of poor play hasn’t lessened the team’s support of manager Bob Melvin. SFGate then picked up Ramos’ comments and took them out of context, publishing a story with the headline: “SF Giants player bashes fans for being ‘against us’ after historic losing skid.”

Prior to Monday’s game, Ramos spoke with reporters to clarify his comments.

“I love the fans and they always show me love in the field,” Ramos said. “I have nothing against them. Every time I’m walking on the streets with my family, they love me and I love them back. All I’m trying to say is in the inner circle — obviously not even you guys that are reporters know what’s going on in the clubhouse — all I want to say is that Bob is a great manager. … I’m just trying to have Bob’s back, I’m just trying to always support (him).

“The fans, like I said, I love them, I have nothing against them. But at the end of the day, what we have in the clubhouse, nobody knows about it. That’s all I was trying to say.”

Once he stepped on the field, Ramos gave Giants fans reason to cheer by hitting a solo homer and establishing an early 1-0 lead.

Rafael Devers followed up with a solo homer of his own, making him and Ramos the first Gants to go back-to-back to begin a road game since Chuck Hiller and Duke Snider. Following Casey Schmitt’s one-out double, Wilmer Flores stunned Petco Park with a two-run homer, the Giants’ third of the inning off Nestor Cortes.

Following his home run in the first, Ramos was partially responsible for taking one away in the second.

In the bottom of the second, the Padres’ Xander Bogaerts hit a towering fly ball to left field. Ramos slowly drifted towards the wall, extending out his right arm so he could feel for the padding. As the ball crashed down to earth, Ramos extended out his left arm. A fan, wearing a black ABBA shirt, also reached out. Ramos made contact with the ball, but the ball deflected off his glove and into the seats for a solo homer.

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When Ramos realized the ball wasn’t in his glove, he raised his right arm to the crowd to suggest that fan interference was at play. Following a lengthy replay review, the call was overturned and Bogaerts was out. The official explanation determined that “the spectator reached out over the field of play and interfered with a live ball.”

Petco Park’s packed house filled the Gaslamp Quarter with a symphony of boos. Ramos proceeded to troll the Padres fans sitting in the left-field bleachers, pointing and laughing at the Friar faithful. The rest of the night, Ramos was greeted with boos every time he stepped to the plate or fielded a fly ball.

Appropriately enough, the Padres’ Ryan O’Hearn flied out to Ramos to end the ballgame.